Publications.

Nature Communications · 15 October 2026

Acute priming using elevated fluid viscosity recovers young-like single-cell surveillance behaviors in aged human T cells. (opens in a new tab)

Dance, Y. W.; Alice Amitrano; Macaluso, N. C.; Min, C.; Thompson, L. T.; Saffron, A. M.; Ge, Z.; Smith, I. M.; Ezenwanne, C.; Milcik, N.; Fennell, A.; Pyndell, K. A.; Szczesny, C.; Langdon, J.; Ursitti, J. A.; Ward, C. W.; Stroka, K. M.; Walston, J. D.; Sun, S. X.; Konstantopoulos, K.; Phillip, J. M.

Alice Amitrano, N. C. Macaluso, C. Min, L. T. Thompson, and A. M. Saffron contributed equally.

Oncogene

Adrenomedullin 2 drives intratumoral cancer cell invasion, intravasation and metastasis. (opens in a new tab)

Stoletov, K.; Karimian, S. S.; Brown, D.; Alice Amitrano; Si, B. R.; Verma, V. M.; Gupta, S.; Bukhari, A. B.; Lamb, S.; Konstantopoulos, K.; Wong, G. K.-S.; Lewis, J. D.

STAR Protocols

Protocol for optogenetic stimulation of cells under physical confinement. (opens in a new tab)

Yuan, Q.; Alice Amitrano; Choudhury, D.; Konstantopoulos, K.

Cancer Research

Not Just Soft: Cell Viscosity Emerges as a Driver of Tumor Cell Dissemination. (opens in a new tab)

Nath, S.; Choudhury, D.; Alice Amitrano; Konstantopoulos, K.

S. Nath, D. Choudhury, and Alice Amitrano contributed equally.

Cell Reports

Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination. (opens in a new tab)

Lee, S. J.; Alice Amitrano; Yuan, Q.; Choudhury, D.; Stoletov, K.; Agarwal, B.; Tran, A.; Godet, I.; McCann, J.; Huizar, R.; Serra, S. A.; Picón-Pagès, P.; Valles, N.; Jeong, S.; Sofou, S.; Fan, C.-M.; Lewis, J. D.; Sun, S. X.; Ewald, A. J.; Gilkes, D. M.; Bajpai, V. K.; Valverde, M. A.; Konstantopoulos, K.

PNAS

Chemical compensation to mechanical loss in cell mechanosensation. (opens in a new tab)

Ni, Q.; Ge, Z.; Sen, A.; Wu, Y.; Fu, J.; Alice Amitrano; Srivastava, N.; Konstantopoulos, K.; Sun, S. X.

Q. Ni, Z. Ge, and A. Sen contributed equally.

Cold Spring Harbor Perspectives in Biology

Engineered in vitro platforms for mechanochemical control of cell migration. (opens in a new tab)

Si, B. R.; Yuan, Q.; Nath, S.; Agarwal, B.; Alice Amitrano; Choudhury, D.; Konstantopoulos, K.

Nature Materials

Cytoplasmic anillin and Ect2 promote RhoA/myosin II-dependent confined migration and invasion. (opens in a new tab)

Tran, A. T.; Wisniewski, E. O.; Mistriotis, P.; Stoletov, K.; Parlani, M.; Alice Amitrano; Ifemembi, B.; Lee, S. J.; Bera, K.; Zhang, Y.; Tuntithavornwat, S.; Afthinos, A.; Kiepas, A.; Agarwal, B.; Nath, S.; Jamieson, J. J.; Zuo, Y.; Habib, D.; Wu, P.-H.; Martin, S. S.; Gerecht, S.; Gu, L.; Lewis, J. D.; Kalab, P.; Friedl, P.; Konstantopoulos, K.

Current Opinion in Cell Biology

Navigating confinement: Mechanotransduction and metabolic adaptation. (opens in a new tab)

Alice Amitrano; Choudhury, D.; Konstantopoulos, K.

Science Advances

Extracellular fluid viscosity regulates human mesenchymal stem cell lineage and function. (opens in a new tab)

Alice Amitrano; Yuan, Q.; Agarwal, B.; Sen, A.; Dance, Y. W.; Zuo, Y.; Phillip, J. M.; Gu, L.; Konstantopoulos, K.

Alice Amitrano and Q. Yuan contributed equally.

Nano Letters

Migration and 3D Traction Force Measurements inside Compliant Microchannels. (opens in a new tab)

Afthinos, A.; Bera, K.; Chen, J.; Ozcelikkale, A.; Alice Amitrano; Choudhury, M. I.; Huang, R.; Pachidis, P.; Mistriotis, P.; Chen, Y.; Konstantopoulos, K.

Science Advances

Ambient-pressure lignin valorization to high-performance polymers by intensified reductive catalytic deconstruction. (opens in a new tab)

O'Dea, R. M.; Pranda, P. A.; Luo, Y.; Alice Amitrano; Ebikade, E. O.; Gottlieb, E. R.; Ajao, O.; Benali, M.; Vlachos, D. G.; Ierapetritou, M.; Epps, T. H. III.

RSC Advances

Estrogenic activity of lignin-derivable alternatives to bisphenol A assessed via molecular docking simulations. (opens in a new tab)

Alice Amitrano; Mahajan, J. S.; Korley, L. T. J.; Epps, T. H. III.

Alice Amitrano and J. S. Mahajan contributed equally.

bioRxiv

Mechanochemical cues control the coupling of metabolic and migratory patterns in cancer. (opens in a new tab)

Alice Amitrano; Choudhury, D.; Ifemembi, B.; Afthinos, A.; Stoletov, K.; Yuan, Q.; Nath, S.; Si, B. R.; Agarwal, B.; Graziano, G.; Gao, J.; Ceisel, A.; Hauf, M.; Sun, S. X.; Ewald, A. J.; Valverde, M. A.; Lewis, J. D.; Mumm, J. S.; Konstantopoulos, K.